Article
Linkage to chromosome 2q32.2-q33.3 in familial serrated neoplasia (Jass syndrome).
Familial cancer - 1 Jun 2011
Roberts Aedan, Nancarrow Derek, Clendenning Mark, Buchanan Daniel D, Jenkins Mark A, Duggan David, Taverna Darin, McKeone Diane, Walters Rhiannon, Walsh Michael D, Young Bruce W, Jass Jeremy R, Rosty Christophe, Gattas Michael, Pelzer Elise, Hopper John L, Goldblatt Jack, George Jill, Suthers Graeme K, Phillips Kerry, Parry Susan, Woodall Sonja, Arnold Julie, Tucker Kathy, Muir Amanda, Drini Musa, Macrae Finlay, Newcomb Polly, Potter John D, Pavluk Erika, Lindblom Annika, Young Joanne P
Abstract excerpt
Causative genetic variants have to date been identified for only a small proportion of familial colorectal cancer (CRC). While conditions such as Familial Adenomatous Polyposis and Lynch syndrome have well defined genetic causes, the search for variants underlying the remainder of familial CRC is plagued by genetic heterogeneity. The recent identification of families with a heritable predisposition to...
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