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Article

Identification of susceptibility genes for cancer in a genome-wide scan: results from the colon neoplasia sibling study.

American journal of human genetics - 1 Mar 2008

Daley Denise, Lewis Susan, Platzer Petra, MacMillen Melissa, Willis Joseph, Elston Robert C, Markowitz Sanford D, Wiesner Georgia L

Abstract excerpt

Colorectal cancer (CRC) is the third most commonly diagnosed cancer in Americans and is the second leading cause of cancer mortality. Only a minority ( approximately 5%) of familial CRC can be explained by known genetic variants. To identify susceptibility genes for familial colorectal neoplasia, the colon neoplasia sibling study conducted a comprehensive, genome-wide linkage scan of 194 kindreds. Clinical...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18313025
DOI: 10.1016/j.ajhg.2008.01.007
PMCID: PMC2427227

Genes

BRCA2
HIC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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