Colorectal cancer genetic variants are also associated with serrated polyposis syndrome susceptibility.

doi:10.1136/jmedgenet-2019-106374

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Article

Colorectal cancer genetic variants are also associated with serrated polyposis syndrome susceptibility.

Journal of medical genetics - 1 Oct 2020

Arnau-Collell Coral, Soares de Lima Yasmin, Díaz-Gay Marcos, Muñoz Jenifer, Carballal Sabela, Bonjoch Laia, Moreira Leticia, Lozano Juan José, Ocaña Teresa, Cuatrecasas Miriam, Díaz de Bustamante Aranzazu, Castells Antoni, Capellà Gabriel, Bujanda Luis, Cubiella Joaquin, Rodríguez-Alcalde Daniel, Balaguer Francesc, Ruiz-Ponte Clara, Valle Laura, Moreno Victor, Castellvi-Bel Sergi

Abstract excerpt

BACKGROUND: Serrated polyposis syndrome (SPS) is a clinical entity characterised by large and/ormultiple serrated polyps throughout the colon and increased risk for colorectal cancer (CRC). The basis for SPS genetic predisposition is largely unknown. Common, low-penetrance genetic variants have been consistently associated with CRC susceptibility, however, their role in SPS genetic predisposition has not been yet...

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Identifiers

PMID: 32170005
DOI: 10.1136/jmedgenet-2019-106374
PMCID: PMC7525772

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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