Article
The identification of colon cancer susceptibility genes by using genome-wide scans.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010
Daley Denise
Abstract excerpt
Recent studies have indicated that in approximately 35% of all colorectal cancer (CRC) cases, the CRC was inherited. Although a number of high-risk familial variants have been identified, these mutations explain <6% of CRC cases; therefore, further genome-wide scans will need to be conducted in the future. There are two popular approaches to genome-wide scans, namely linkage and association. The linkage approach...
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