Article
Genetic predisposition to colorectal cancer: where we stand and future perspectives.
World journal of gastroenterology - 7 Aug 2014
Valle Laura
Abstract excerpt
The development of colorectal cancer (CRC) can be influenced by genetic factors in both familial cases and sporadic cases. Familial CRC has been associated with genetic changes in high-, moderate- and low-penetrance susceptibility genes. However, despite the availability of current gene-identification techniques, the genetic causes of a considerable proportion of hereditary cases remain unknown. Genome-wide...
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