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Article

Mineralocorticoid receptor gene variants as determinants of HPA axis regulation and behavior.

Endocrine development - 1 Jan 2011

DeRijk Roel H, de Kloet E Ron, Zitman Frans G, van Leeuwen Nienke

Abstract excerpt

We tested if common mineralocorticoid receptor (MR) gene variants contribute to the variability in neuroendocrine control and behavioral reactivity as observed in humans. For that purpose we screened for genetic variability and tested functionality of the identified human MR gene variants in vitro. Four haplotypes were tested for transactivational capacity in vitro and showed profound significant differences when...

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Identifiers

PMID: 21164267
DOI: 10.1159/000321235

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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