Article
Influence of A9 region mutation in EphB2 gene in the prognosis of patients with colorectal adenocarcinoma.
Annals of surgical oncology - 1 May 2011
Vidaurreta M, Rafael S, Veganzones S, de la Orden V, Fernández C, Gómez-Casaseca R, Cerdán J, Maestro M
Abstract excerpt
BACKGROUND: EphB2 is a transmembrane glycoprotein implicated in the regulation of cell growth, differentiation, and motility. It has been proposed as a tumor suppressor gene, and the role of EphB2 protein in tumorogenesis has been demonstrated. The aim of this study was to test the influence of mutation of A9 region in EphB2 gene in the prognosis of patients with sporadic CCR. MATERIALS AND METHODS: A total of...
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