Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Preferential induction of EphB4 over EphB2 and its implication in colorectal cancer progression.

Cancer research - 1 May 2009

Kumar S Ram, Scehnet Jeffrey S, Ley Eric J, Singh Jasbir, Krasnoperov Valery, Liu Ren, Manchanda Parmeet K, Ladner Robert D, Hawes Debra, Weaver Fred A, Beart Robert W, Singh Gagandeep, Nguyen Cu, Kahn Michael, Gill Parkash S

Abstract excerpt

The receptor tyrosine kinase EphB2 is expressed by colon progenitor cells; however, only 39% of colorectal tumors express EphB2 and expression levels decline with disease progression. Conversely, EphB4 is absent in normal colon but is expressed in all 102 colorectal cancer specimens analyzed, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta Catenin
Share to Fluorescent Antibody Technique

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HT29 Cells

Share to Immunoblotting

Share to Mice, Inbred BALB C

Share to Mice, Nude

Share to RNA, Small Interfering

Share to Transplantation, Heterologous

Source

Identifiers

PMID: 19366806
DOI: 10.1158/0008-5472.CAN-08-3232

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19366806-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Preferential induction of EphB4 over EphB2 and its implication in colorectal cancer progression.PMID 19366806Read ↗

EphB receptor activity suppresses colorectal cancer progression.Semantic proximity Read ↗

EphB6 overexpression and Apc mutation together promote colorectal cancer.Semantic proximity Read ↗

EphA3 promotes malignant transformation of colorectal epithelial cells by upregulating oncogenic pathways.Semantic proximity Read ↗

Loss of EphA2 receptor tyrosine kinase reduces ApcMin/+ tumorigenesis.Semantic proximity Read ↗

EZH2 inhibition promotes ANGPTL4/CREB1 to suppress the progression of ulcerative colitisSemantic proximity Read ↗

EphB6 deficiency in intestinal neurons promotes tumor growth in colorectal cancer by neurotransmitter GABA signalingSemantic proximity Read ↗

Influence of A9 region mutation in EphB2 gene in the prognosis of patients with colorectal adenocarcinoma.Semantic proximity Read ↗

Colorectal cancer-associated mutations impair EphB1 kinase function.Semantic proximity Read ↗

Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activitySemantic proximity Read ↗

Differential Expression of the Receptor Tyrosine Kinase EphB4 and Its Ligand Ephrin-B2 During Human Placental DevelopmentSemantic proximity Read ↗

ZEB1 Promotes Invasiveness of Colorectal Carcinoma Cells through the Opposing Regulation of uPA and PAI-1Semantic proximity Read ↗

Interaction of endocannabinoid system and steroid Hormones in the control of colon cancer cell growthSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.