Article
A9 region in EPHB2 mutation is frequent in tumors with microsatellite instability. Analysis of prognosis.
Anticancer research - 1 Nov 2013
Rafael Sara, Vidaurreta Marta, Veganzones Silvia, De La Orden Virgnia, Mediero Beatriz, Gutierrez Maria Luisa, Maestro Maria Luisa
Abstract excerpt
AIM: The aim of the present study was to determine the relation of EPH tyrosine kinase receptor B2 (EPHB2) A9 region mutation and microsatellite instability (MSI); and to analyze their influence in prognosis of patients with sporadic colorectal cancer (CRC). PATIENTS AND METHODS: A total of 481 patients with CRC were examined. MSI (NCI criteria) and EPHB2 were analyzed using PCR and fragment analysis software....
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