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Article

Absence of association between TNF-α polymorphism and cerebral large-vessel abnormalities in adults with sickle cell anemia.

Acta haematologica - 1 Jan 2011

Vicari Perla, Silva Gisele Sampaio, Nogutti Maria Aparecida Eiko, Neto Faustino Moreira, dos Santos Normélia Jesus, Massaro Ayrton Roberto, Figueiredo Maria Stella

Abstract excerpt

Stroke is a serious complication of sickle cell anemia (SCA) affecting children and adults. Recent reports suggested that tumor necrosis factor-α (TNF-α) (-308) polymorphism is an important risk factor for stroke in children with SCA. The role of TNF-α polymorphism in the frequency of brain magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA) abnormalities in adults with SCA is still...

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Identifiers

PMID: 21160173
DOI: 10.1159/000321935

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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