Article
Reticulocyte count is the most important predictor of acute cerebral ischemia and high-risk transcranial Doppler in a newborn cohort of 395 children with sickle cell anemia.
Annals of hematology - 1 Oct 2016
Belisário André Rolim, Sales Rahyssa Rodrigues, Toledo Nayara Evelin, Muniz Maristela Braga de Sousa Rodrigues, Velloso-Rodrigues Cibele, Silva Célia Maria, Viana Marcos Borato
Abstract excerpt
Stroke is a severe clinical manifestation of sickle cell anemia (SCA). Despite the prognostic relevance of transcranial Doppler (TCD), more accurate tools to assess stroke risk in children with SCA are required. Here, we describe the effect of clinical, laboratory, and molecular features on the risk of stroke and high-risk TCD in children from the newborn cohort of Minas Gerais, Brazil. Outcomes studied were...
Topics
- Acute Chest Syndrome
- Acute Disease
- Anemia, Sickle Cell
- Brain Ischemia
- Child
- Female
- Follow-Up Studies
- Haplotypes
- Humans
- Incidence
- Infant, Newborn
- Leukocyte Count
- Male