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Article

Gene interactions and stroke risk in children with sickle cell anemia.

Blood - 15 Mar 2004

Hoppe Carolyn, Klitz William, Cheng Suzanne, Apple Ray, Steiner Lori, Robles Lara, Girard Tom, Vichinsky Elliott, Styles Lori

Abstract excerpt

Stroke is a devastating complication of sickle cell anemia (SCA), affecting up to 30% of children with the disease. Despite the relative frequency of stroke in SCA, few predictors of risk exist. Because stroke in SCA is likely a multifactorial disease, analysis of the combined effect of multiple genetic variants may prove more successful than evaluation of individual candidate genes. We genotyped 230 children...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Anemia, Sickle Cell

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Share to Receptors, Interleukin-4

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Source

Identifiers

PMID: 14615367
DOI: 10.1182/blood-2003-09-3015

Genes

TNF
ADRB2
LDLR
VCAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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