Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel multilocus genotyping assay to identify genetic predictors of stroke in sickle cell anaemia.

British journal of haematology - 1 Sept 2001

Hoppe C, Cheng S, Grow M, Silbergleit A, Klitz W, Trachtenberg E, Erlich H, Vichinsky E, Styles L

Abstract excerpt

We describe a novel multilocus genotyping assay permitting simultaneous identification of 60 candidate markers for stroke in sickle cell anaemia (SCA). Based on cerebral magnetic resonance imaging (MRI), 69 patients were divided into stroke and control groups. The variant allele, CBS 278thr, showed protection from stroke, whereas the apoE3 allele showed a trend towards association with increased stroke risk....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia, Sickle Cell
Share to Apolipoproteins E

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Cystathionine beta-Synthase

Share to Genetic Markers

Share to Odds Ratio

Share to Stroke

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 11553004
DOI: 10.1046/j.1365-2141.2001.02997.x

Genes

CBS
CETP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel multilocus genotyping assay to identify genetic predictors of stroke in sickle cell anaemia.PMID 11553004Read ↗

Genetic predictors for stroke in children with sickle cell anemia.Semantic proximity Read ↗

Genetic Variants Associated with the Risk of Stroke in Sickle Cell Anemia: Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Genetic variants associated with the risk of stroke in sickle cell disease: a systematic review and meta-analysisSemantic proximity Read ↗

Gene interactions and stroke risk in children with sickle cell anemia.Semantic proximity Read ↗

Candidate genetic risk factors of stroke: results of a multilocus genotyping assay.Semantic proximity Read ↗

Stroke risk in siblings with sickle cell anemia.Semantic proximity Read ↗

Confirmation of an association between the TNF(-308) promoter polymorphism and stroke risk in children with sickle cell anemia.Semantic proximity Read ↗

Influence of the βs haplotype and α-thalassemia on stroke development in a Brazilian population with sickle cell anaemia.Semantic proximity Read ↗

Genetic dissection and prognostic modeling of overt stroke in sickle cell anemia.Semantic proximity Read ↗

Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen.Semantic proximity Read ↗

Polymorphisms and expression of MMPs-TIMPs genes associated with cerebral ischemic stroke in young patients with sickle cell anemiaSemantic proximity Read ↗

A-296G variant of THBS1 gene (rs1478605) is associated with a lower frequency of stroke in a Brazilian population with sickle cell anemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.