Article
Variants and haplotypes of TCF7L2 are associated with β-cell function in patients with newly diagnosed type 2 diabetes: the Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 1.
The Journal of clinical endocrinology and metabolism - 1 Feb 2011
Bonetti S, Trombetta M, Malerba G, Boselli L, Trabetti E, Muggeo M, Stoico V, Negri C, Pignatti P F, Bonora E, Bonadonna R C
Abstract excerpt
CONTEXT: Intronic variants of TCF7L2 are confirmed genetic risk factors for type 2 diabetes and are associated to alterations in beta cell function in nondiabetic individuals. OBJECTIVE: The objective of the study was to test whether TCF7L2 variability may affect β-cell function also in patients...
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