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Article

New gene variants alter type 2 diabetes risk predominantly through reduced beta-cell function.

Current opinion in clinical nutrition and metabolic care - 1 Jul 2008

Perry John R B, Frayling Timothy M

Abstract excerpt

PURPOSE OF REVIEW: Over the past 18 months, the number of gene loci robustly associated with type 2 diabetes has risen from three to 18. In this study, we focus on explaining the genome-wide approach that has led to most of these discoveries and discuss some of the early insights the new gene loci have provided into the aetiology of type 2 diabetes. RECENT FINDINGS: Recent genome-wide association studies have...

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Topics

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Share to Diabetes Mellitus, Type 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genome, Human

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Source

Identifiers

PMID: 18541994
DOI: 10.1097/MCO.0b013e32830349a1

Genes

CDKAL1
FTO
HHEX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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