Article
Variants of the TCF7L2 gene are associated with beta cell dysfunction and confer an increased risk of type 2 diabetes mellitus in the ULSAM cohort of Swedish elderly men.
Diabetologia - 1 Sept 2007
Dahlgren A, Zethelius B, Jensevik K, Syvänen A-C, Berne C
Abstract excerpt
AIMS/HYPOTHESIS: In a population-based cohort of elderly men with well-defined phenotypes and biochemical markers related to type 2 diabetes mellitus, we analysed two single nucleotide polymorphisms (SNPs), rs7903146 and rs12255372, in the transcription factor 7-like 2 gene (TCF7L2), which are associated with an increased risk of type 2 diabetes mellitus. MATERIALS AND METHODS: The 1,142 subjects were from the...
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