Article
The TCF7L2 diabetes risk variant is associated with HbA₁(C) levels: a genome-wide association meta-analysis.
Annals of human genetics - 1 Nov 2010
Franklin Christopher S, Aulchenko Yurii S, Huffman Jennifer E, Vitart Veronique, Hayward Caroline, Polašek Ozren, Knott Sara, Zgaga Lina, Zemunik Tatijana, Rudan Igor, Campbell Harry, Wright Alan F, Wild Sarah H, Wilson James F
Abstract excerpt
Genome-wide association (GWA) studies have identified around 20 common genetic variants influencing the risk of type 2 diabetes (T2D). Likewise, a number of variants have been associated with diabetes-related quantitative glycaemic traits, but to date the overlap between these genes and variants has been low. The majority of genetic studies have focused on fasting plasma glucose levels; however, this measure is...
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