Article
Association of EMCN with susceptibility to rheumatoid arthritis in a Japanese population.
The Journal of rheumatology - 1 Feb 2011
Nishimoto Kazumasa, Ikari Katsunori, Kaneko Hirotaka, Tsukahara So, Kochi Yuta, Yamamoto Kazuhiko, Nakamura Yusuke, Toyama Yoshiaki, Taniguchi Atsuo, Yamanaka Hisashi, Momohara Shigeki
Abstract excerpt
OBJECTIVE: Endomucin, an endothelial-specific sialomucin, is thought to facilitate "lymphocyte homing" to synovial tissues, resulting in the major histopathologies of rheumatoid arthritis (RA). We examined the association between RA susceptibility and the gene coding endomucin, EMCN. METHODS: Association studies were conducted with 2 DNA sample sets (initial set of 1504 patients, 752 controls; and validation set,...
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