Article
Particular association of clinical and genetic features with autoimmunity to citrullinated α-enolase in rheumatoid arthritis.
Arthritis and rheumatism - 1 Mar 2011
Montes Ariana, Dieguez-Gonzalez Rebeca, Perez-Pampin Eva, Calaza Manuel, Mera-Varela Antonio, Gomez-Reino Juan J, Gonzalez Antonio
Abstract excerpt
OBJECTIVE: To confirm that the presence of anti-citrullinated α-enolase peptide 1 (anti-CEP-1) antibodies identifies a subgroup of patients with rheumatoid arthritis (RA). METHODS: DNA and serum samples were obtained from 451 patients with RA and 279 healthy control subjects, all of whom were of Spanish ancestry. Antibodies to cyclic citrullinated peptide (CCP) and CEP-1 were measured by enzyme-linked...
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