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Article

Association of the AIRE gene with susceptibility to rheumatoid arthritis in a European population: a case control study.

Arthritis research & therapy - 15 Jan 2013

García-Lozano José-Raúl, Torres-Agrela Belén, Montes-Cano Marco-Antonio, Ortiz-Fernández Lourdes, Conde-Jaldón Marta, Teruel María, García Alicia, Núñez-Roldán Antonio, Martín Javier, González-Escribano María-Francisca

Abstract excerpt

INTRODUCTION: AIRE is a transcriptional regulator playing a functional role in thymocyte education and negative selection by controlling the expression of peripheral antigens in the thymus. Recently, the AIRE gene was identified as a genetic risk factor for rheumatoid arthritis (RA) in genome wide association (GWA) studies performed in the Japanese population. According to the available data this association is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23320549
DOI: 10.1186/ar4141
PMCID: PMC3672784

Genes

AIRE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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