Article
[Association between the synovial expression of cyclic citrullinated peptide and susceptibility variants of HLA-DRB1 shared epitope alleles and PADI 4 gene single nucleotide polymorphisms in patients with rheumatoid arthritis].
Zhonghua yi xue za zhi - 19 Jun 2012
Li Hong-bin, Tie Ning, Jia Yong-feng, Shi Lin, Su Yan, Zhang Gui-zhi, Wang Yong, Bai Li-jie, Zhao Jing, Wang Jing, Xiao Zhen
Abstract excerpt
OBJECTIVE: To analyze the association between the synovial expression of cyclic citrullinated peptide (CCP) and susceptibility variants of HLA-DRB1 shared epitope (SE) alleles and/or peptidylarginine deiminase 4 (PADI4) gene single nucleotide polymorphisms (SNP) in patients with rheumatoid arthritis (RA). METHODS: From October 2008 to December 2011, 53 RA patients and 42 controls were enrolled. The expression of...
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