Article
Association between single-nucleotide polymorphisms in the SEC8L1 gene, which encodes a subunit of the exocyst complex, and rheumatoid arthritis in a Japanese population.
Arthritis and rheumatism - 1 May 2005
Hamada Daisuke, Takata Yoichiro, Osabe Dai, Nomura Kyoko, Shinohara Syuichi, Egawa Hiroshi, Nakano Syunji, Shinomiya Fumio, Scafe Charles R, Reeve Vincent M, Miyamoto Tatsuro, Moritani Maki, Kunika Kiyoshi, Inoue Hiroshi, Yasui Natsuo, Itakura Mitsuo
Abstract excerpt
OBJECTIVE: To identify rheumatoid arthritis (RA) susceptibility genes in a Japanese population by conducting a large-scale case-control association analysis and linkage disequilibrium (LD) mapping on chromosome 7q31-34, a candidate susceptibility locus identified in a preliminary genome-wide scan in 53 Japanese families, using single-nucleotide polymorphisms (SNPs). METHODS: We prepared 728 dense, evenly spaced...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.