Article
Association study of polymorphisms between the Radixin gene and rheumatoid arthritis in a Korean population.
Genetics and molecular research : GMR - 9 May 2014
Kim H-K, Joo J-S, Lee H-Y, Kwon J-T, Sohn D-R, Hong S-J, Kim H-J
Abstract excerpt
Radixin (RDX) is part of the ezrin-radixin-moesin (ERM) protein family. It functions as a membrane-cytoskeletal linker in actin-rich cell surface structures and is thought to be essential for cortical cytoskeleton organization, cell motility, adhesion, and proliferation. An increase in phosphorylated ERM in fibroblast-like synoviocytes contributes to rheumatoid arthritis (RA) synovial hyperplasia. We examined the...
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