Article
Dense mapping of IL18 shows no association in SLE.
Human molecular genetics - 1 Mar 2011
Guerra Sandra G, Morris David L, Gateva Vesela, Graham Robert R, Vyse Timothy J, Cunninghame Graham Deborah S
Abstract excerpt
Systemic lupus erythematosus (SLE) is an autoimmune disease which behaves as a complex genetic trait. At least 20 SLE risk susceptibility loci have been mapped using both candidate gene and genome-wide association strategies. The gene encoding the pro-inflammatory cytokine, IL18, has been reporte...
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