Article
Chromosome 17p12-q11 harbors susceptibility loci for systemic lupus erythematosus.
Human genetics - 1 Aug 2004
Johansson Cecilia M, Zunec Renata, García Mercedes A, Scherbarth Hugo R, Tate Guillermo A, Paira Sergio, Navarro Sandra M, Perandones Carlos E, Gamron Susana, Alvarellos Alejandro, Graf Cesar E, Manni Jorge, Berbotto Guillermo A, Palatnik Simon A, Catoggio Luis J, Battagliotti Cristina G, Sebastiani Gian Domenico, Migliaresi Sergio, Galeazzi Mauro, Pons-Estel Bernardo A, Alarcón-Riquelme Marta E
Abstract excerpt
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the presence of autoantibodies against intracellular components, the formation of immune complexes, and inflammation in various organs, typically the skin and kidney glomeruli. The etiology of the disease is not well understood but is most likely the result of the interaction between genetic and environmental factors. In order to...
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