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Article

Catechol-O-methyltransferase Val(158)Met association with parahippocampal physiology during memory encoding in schizophrenia.

Psychological medicine - 1 Aug 2011

Di Giorgio A, Caforio G, Blasi G, Taurisano P, Fazio L, Romano R, Ursini G, Gelao B, Bianco L Lo, Papazacharias A, Sinibaldi L, Popolizio T, Bellomo A, Bertolino A

Abstract excerpt

BACKGROUND: Catechol-O-methyltransferase (COMT) Val158Met has been associated with activity of the mesial temporal lobe during episodic memory and it may weakly increase risk for schizophrenia. However, how this variant affects parahippocampal and hippocampal physiology when dopamine transmission is perturbed is unclear. The aim of the present study was to compare the effects of the COMT Val158Met genotype on...

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Identifiers

PMID: 21144115
DOI: 10.1017/S0033291710002278

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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