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Article

Differences in IGFBP-3 regulation between young healthy women from BRCAX families and those belonging to BRCA1/2 families.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Jun 2006

Jernström Helena, Sellberg Gunilla, Borg Ake, Olsson Hakan

Abstract excerpt

Since IGF-1 and IGFBP-3 levels have been implicated in premenopausal breast cancer, we aimed to explore whether there were differences in IGF-1 and IGFBP-3 regulation between women from BRCA1/2 families and from families in which no BRCA1/2 mutations could be detected, that is, from BRCAX families. One hundred and one healthy 18-40-year-old women from hereditary breast cancer families with known BRCA1/2 mutations...

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Source

Identifiers

PMID: 16679866
DOI: 10.1097/01.cej.0000203615.77183.97

Genes

BRCA1
IGFBP3
IGF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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