Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of an MDR1 gene (C3435T) polymorphism with acute leukemia in India.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2010

Rao D Nageswara, Anuradha C, Vishnupriya S, Sailaja K, Surekha D, Raghunadharao D, Rajappa Senthil

Abstract excerpt

The multidrug resistance (MDR1) gene product P-glycoprotein is a membrane bound protein that functions as an ATP-dependent efflux pump, transporting exogenous and endogenous substrates from the cells. Since it plays an important role in chemotherapy, there is an increasing interest in the possible significance of genetic variation in MDR1. Our main objective was to study the MDR1gene polymorphism at C3435T with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Binding Cassette Transporter, Subfamily B
Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chi-Square Distribution

Share to Genes, MDR

Share to Leukemia, Myeloid, Acute

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Share to Treatment Outcome

Source

Identifiers

PMID: 21133625

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of an MDR1 gene (C3435T) polymorphism with acute leukemia in India.PMID 21133625Read ↗

Functional C3435T polymorphism of MDR1 gene: an impact on genetic susceptibility and clinical outcome of childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

Variant genotypes of MDR1 C3435T increase the risk of leukemia: evidence from 10 case-control studies.Semantic proximity Read ↗

MDR1 C3435T and C1236T polymorphisms: association with high-risk childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

Association between the MDR1 gene variant C3435T and risk of leukaemia: a meta-analysis.Semantic proximity Read ↗

Analysis of single nucleotide polymorphism C3435T of the multidrug resistance gene MDR1 in acute lymphoblastic leukemia.Semantic proximity Read ↗

MDR1 C3435T polymorphism and childhood acute lymphoblastic leukemia susceptibility: an updated meta-analysis.Semantic proximity Read ↗

High expression levels and the C3435T SNP of the ABCB1 gene are associated with lower survival in adult patients with acute myeloblastic leukemia in Mexico City.Semantic proximity Read ↗

Multi-drug resistance 1 genetic polymorphism and prediction of chemotherapy response in Hodgkin's Lymphoma.Semantic proximity Read ↗

MDR1 gene C3435T polymorphism in chronic hepatitis C patients.Semantic proximity Read ↗

MDR1 C3435T polymorphism in patients with breast cancer.Semantic proximity Read ↗

Multi-drug transporter MDR1 gene polymorphism and prognosis in adult acute lymphoblastic leukemia.Semantic proximity Read ↗

Identification of polymorphisms on the MDR1 gene among Turkish population and their effects on multidrug resistance in acute leukemia patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.