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Article

Multi-drug resistance 1 genetic polymorphism and prediction of chemotherapy response in Hodgkin's Lymphoma.

Journal of experimental & clinical cancer research : CR - 16 Jul 2011

Mhaidat Nizar M, Alshogran Osama Y, Khabour Omar F, Alzoubi Karem H, Matalka Ismail I, Haddadin William J, Mahasneh Ibraheem O, Aldaher Ahmad N

Abstract excerpt

BACKGROUND: The human multi-drug resistance gene (MDR1), which encodes the major trans-membrane transporter P-glycoprotein (P-gp), was found to be associated with susceptibility to cancer and response to chemotherapy. The C3435T Polymorphism of MDR1 gene was correlated with expression levels and functions of P-gp. Here, we studied the association between MDR1 C3435T polymorphism and susceptibility to Hodgkin...

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Identifiers

PMID: 21762523
DOI: 10.1186/1756-9966-30-68
PMCID: PMC3154152

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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