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Article

MDR1 gene C3435T polymorphism in chronic hepatitis C patients.

Microbial pathogenesis - 1 Jan 2018

Parsa Nahad Mehdi, Makvandi Manoochehr, Teimoori Ali, Jalilian Shahram, Kayedani Gholam Abbas, Mahmoodi Sara

Abstract excerpt

BACKGROUND: MDR1 is a highly polymorphic gene that encodes P-glycoprotein (P-gp). This protein anchor to the cell membrane and transports toxins, xenobiotic, chemicals, and drugs from the intracellular to extracellular and thus protect cells. Polymorphism of the MDR1 gene seems to be effective in gene expression and response to treatment. Since one of the main mechanisms of drug resistance is the removal of the...

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Identifiers

PMID: 29155127
DOI: 10.1016/j.micpath.2017.11.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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