Article
The XRCC1 and TP53 gene polymorphisms are associated with advanced-stage disease and early distant metastasis at diagnosis in non-small cell lung cancer.
Journal of cancer research and therapeutics - 1 Jan 2000
Karaağaç Mustafa, Geredeli Çağlayan, Yıldırım Mahmut Selman, Altınok Tamer, Dede İsa, İnal Ali, Zamani Ayşe Gül, Kaya Buğra, Demirkazık Ahmet, Artaç Mehmet
Abstract excerpt
Background: Studies on single nucleotide polymorphisms (SNPs) in non-small cell lung cancer (NSCLC) suggest that DNA repair capacity may have prognostic implications for disease recurrence and survival. However, there is no study investigating the relationship between SNPs and the risk of metastasis at the time of initial diagnosis in patients with NSCLC. Objective: This study aimed to investigate the potential...
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