Article
Molecular epidemiology of non-small cell lung cancer.
Seminars in respiratory and critical care medicine - 1 Jun 2005
Liu Geoffrey, Zhou Wei, Christiani David C
Abstract excerpt
Although smoking is the primary risk factor for most lung cancers, genetic predisposition may play an important role. Familial aggregation studies suggest a greater genetic component in the risk for younger individuals developing lung cancer, for lifetime nonsmokers, and possibly for women. Low-penetrance, high-prevalence polymorphic genes may explain part of this genetic predisposition. Functional polymorphisms...
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