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Article

Gene expression in skin and lymphoblastoid cells: Refined statistical method reveals extensive overlap in cis-eQTL signals.

American journal of human genetics - 10 Dec 2010

Ding Jun, Gudjonsson Johann E, Liang Liming, Stuart Philip E, Li Yun, Chen Wei, Weichenthal Michael, Ellinghaus Eva, Franke Andre, Cookson William, Nair Rajan P, Elder James T, Abecasis Gonçalo R

Abstract excerpt

Psoriasis, an immune-mediated, inflammatory disease of the skin and joints, provides an ideal system for expression quantitative trait locus (eQTL) analysis, because it has a strong genetic basis and disease-relevant tissue (skin) is readily accessible. To better understand the role of genetic variants regulating cutaneous gene expression, we identified 841 cis-acting eQTLs using RNA extracted from skin biopsies...

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Identifiers

PMID: 21129726
DOI: 10.1016/j.ajhg.2010.10.024
PMCID: PMC2997368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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