Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An integrated analysis of public genomic data unveils a possible functional mechanism of psoriasis risk via a long-range ERRFI1 enhancer.

BMC medical genomics - 22 Jan 2020

Kubota Naoto, Suyama Mikita

Abstract excerpt

BACKGROUND: Psoriasis is a chronic inflammatory skin disease, for which genome-wide association studies (GWAS) have identified many genetic variants as risk markers. However, the details of underlying molecular mechanisms, especially which variants are functional, are poorly understood. METHODS: We utilized a computational approach to survey psoriasis-associated functional variants that might affect protein...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Databases, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enhancer Elements, Genetic

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Psoriasis

Share to Quantitative Trait Loci

Share to Tumor Suppressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 31969149
DOI: 10.1186/s12920-020-0662-9
PMCID: PMC6977261

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An integrated analysis of public genomic data unveils a possible functional mechanism of psoriasis risk via a long-range ERRFI1 enhancer.PMID 31969149Read ↗

A catalog of potential putative functional variants in psoriasis genome-wide association regions.Semantic proximity Read ↗

Dissection of a non-coding risk locus at 1p36.23 identifies <i>ERRFI1</i> as a novel gene in the pathogenesis of psoriasis and psoriatic arthritisSemantic proximity Read ↗

Sequencing-based approach identified three new susceptibility loci for psoriasis.Semantic proximity Read ↗

Genetic study of psoriasis highlights its close link with socio-economic status and affective symptomsSemantic proximity Read ↗

Genetic Study of Psoriasis Highlights its Close Link with Socioeconomic Status and Affective Symptoms.Semantic proximity Read ↗

Identification of a missense variant in LNPEP that confers psoriasis risk.Semantic proximity Read ↗

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.Semantic proximity Read ↗

Disentangling the complexity of psoriasis in the post-genome-wide association era.Semantic proximity Read ↗

A novel polygenic risk score model based on the protein interactions: An application on psoriasisSemantic proximity Read ↗

Filter-free exhaustive odds ratio-based genome-wide interaction approach pinpoints evidence for interaction in the HLA region in psoriasis.Semantic proximity Read ↗

Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis.Semantic proximity Read ↗

Genome-wide meta-analysis and integrative fine-mapping identify novel susceptibility loci and effector genes in psoriatic arthritisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.