Article
Leptotene/zygotene chromosome movement via the SUN/KASH protein bridge in Caenorhabditis elegans.
PLoS genetics - 24 Nov 2010
Baudrimont Antoine, Penkner Alexandra, Woglar Alexander, Machacek Thomas, Wegrostek Christina, Gloggnitzer Jiradet, Fridkin Alexandra, Klein Franz, Gruenbaum Yosef, Pasierbek Pawel, Jantsch Verena
Abstract excerpt
The Caenorhabditis elegans inner nuclear envelope protein matefin/SUN-1 plays a conserved, pivotal role in the process of genome haploidization. CHK-2-dependent phosphorylation of SUN-1 regulates homologous chromosome pairing and interhomolog recombination in Caenorhabditis elegans. Using time-lapse microscopy, we characterized the movement of matefin/SUN-1::GFP aggregates (the equivalent of chromosomal...
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