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Article

Meiotic chromosome homology search involves modifications of the nuclear envelope protein Matefin/SUN-1.

Cell - 25 Nov 2009

Penkner Alexandra M, Fridkin Alexandra, Gloggnitzer Jiradet, Baudrimont Antoine, Machacek Thomas, Woglar Alexander, Csaszar Edina, Pasierbek Pawel, Ammerer Gustav, Gruenbaum Yosef, Jantsch Verena

Abstract excerpt

Genome haploidization during meiosis depends on recognition and association of parental homologous chromosomes. The C. elegans SUN/KASH domain proteins Matefin/SUN-1 and ZYG-12 have a conserved role in this process. They bridge the nuclear envelope, connecting the cytoplasm and the nucleoplasm to transmit forces that allow chromosome movement and homolog pairing and prevent nonhomologous synapsis. Here, we show...

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PMID: 19913286
DOI: 10.1016/j.cell.2009.10.045

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Meiotic chromosome homology search involves modifications of the nuclear envelope protein Matefin/SUN-1.PMID 19913286Read ↗

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