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Article

toca-1 is in a novel pathway that functions in parallel with a SUN-KASH nuclear envelope bridge to move nuclei in Caenorhabditis elegans.

Genetics - 1 Jan 2013

Chang Yu-Tai, Dranow Daniel, Kuhn Jonathan, Meyerzon Marina, Ngo Minh, Ratner Dmitry, Warltier Karin, Starr Daniel A

Abstract excerpt

Moving the nucleus to an intracellular location is critical to many fundamental cell and developmental processes, including cell migration, differentiation, fertilization, and establishment of cellular polarity. Bridges of SUN and KASH proteins span the nuclear envelope and mediate many nuclear positioning events, but other pathways function independently through poorly characterized mechanisms. To identify and...

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Identifiers

PMID: 23150597
DOI: 10.1534/genetics.112.146589
PMCID: PMC3527245

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