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Article

Spatial navigation and APOE in amnestic mild cognitive impairment.

Neuro-degenerative diseases - 1 Jan 2011

Laczó Jan, Andel Ross, Vlček Kamil, Macoška Václav, Vyhnálek Martin, Tolar Martin, Bojar Martin, Hort Jakub

Abstract excerpt

BACKGROUND: The effect of APOE ε4 allele (ε4) on spatial navigation in amnestic mild cognitive impairment (aMCI) is unknown. OBJECTIVE: Our purpose was to examine the characteristics of spatial navigation impairment in ε4-positive (ε4+) and ε4-negative (ε4-) aMCI subgroups. METHODS: Blood samples were collected to determine the APOE genotype. A total of 34 aMCI patients were stratified into aMCI-ε4- (n = 23) and...

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Source

Identifiers

PMID: 21124005
DOI: 10.1159/000321581

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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