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Article

Allocentric and Egocentric Spatial Processing in Middle-Aged Adults at High Risk of Late-Onset Alzheimer's Disease: The PREVENT Dementia Study.

Journal of Alzheimer's disease : JAD - 1 Jan 2018

Ritchie Karen, Carrière Isabelle, Howett David, Su Li, Hornberger Michael, O'Brien John T, Ritchie Craig W, Chan Dennis

Abstract excerpt

Impairments in spatial processing due to hippocampal degeneration have been observed in the years immediately preceding the diagnosis of Alzheimer's disease (AD) dementia. The demonstration of changes in spatial processing in preceding decades would provide a cognitive marker for pre-clinical AD and an outcome measure for early intervention trials. The present study examined allocentric and egocentric spatial...

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PMID: 30103333
DOI: 10.3233/JAD-180432

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