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Article

[Study on NPM1 gene mutations in childhood acute myeloid leukemia].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Jul 2010

Zhou Min, Tang Jing-Yan, Xue Hui-Liang, Liu Yin, Pan Ci, Chen Jing, Dong Lu, Shen Shu-Hong

Abstract excerpt

OBJECTIVE: To examine the incidence and clinical significance of NPM1 mutations in childhood acute myeloid leukemia (AML) patients. METHODS: NPM1 mutations of 70 newly diagnosed childhood AML were detected by high resolution melting (HRM) analysis on the LightCycler 480. The incidence and clinical significance were analyzed. RESULTS: NPM1 mutations were identified in 32 (45.7%) of the 70 AML children. There was...

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Source

Identifiers

PMID: 21122395

Genes

NPM1
EFS
PML

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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