[Immunophenotypic and clinical characteristic analysis of NPM1 mutated acute myeloid leukemia with a normal karyotype].

doi:10.7534/j.issn.1009-2137.2013.06.004

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Article

[Immunophenotypic and clinical characteristic analysis of NPM1 mutated acute myeloid leukemia with a normal karyotype].

Zhongguo shi yan xue ye xue za zhi - 1 Dec 2013

Liu Yan-Rong, Lai Yue-Yun, Chang Yan, Ruan Guo-Rui, Qin Ya-Zhen, Wang Ya-Zhe, Zhu Hong-Hu, Shi Hong-Xia, Jiang Bin, Jiang Hao, Jiang Qian, Hao Le, Li Jin-Lan

Abstract excerpt

This study was purposed to compare the immunophenotypic and clinical characteristics of NPM1 mutated acute myeloid leukemia with a normal karyotype under the similar constituent ratio of FAB subtypes. Immunophenotyping and NPM1 gene mutation type-A,B and D and other leukemic related fusion genes were detected by multiparameter flow cytometry and real time RT-PCR or PCR, respectively. 77 AML patients with a normal...

Topics

Adolescent
Adult
Aged
Child
Child, Preschool
Female
Flow Cytometry
Humans
Immunophenotyping
Karyotype
Leukemia, Myeloid, Acute

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Mutation

Nuclear Proteins

Nucleophosmin

Young Adult

Source

Open in PubMed

Identifiers

PMID: 24370016
DOI: 10.7534/j.issn.1009-2137.2013.06.004

Genes

NPM1
FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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