Article
[NPM1 and CEBPA mutations in pediatric cytogenetically normal acute myeloid leukemia].
Zhonghua er ke za zhi = Chinese journal of pediatrics - 1 Apr 2014
Ruan Min, Zhang Li, Han Cong, Liu Xiaoming, Ai Xiaofei, Zhang Jiayuan, Liu Tianfeng, Yang Wenyu, Chen Xiaojuan, Guo Ye, Wang Shuchun, Li Qinghua, Zou Yao, Chen Yumei, Zhu Xiaofan
Abstract excerpt
OBJECTIVE: To evaluate the frequency of the nucleophosmin (NPM1) gene and the CCAAT/enhancer binding protein α gene (CEBPA) through polymerase chain reaction (PCR) array in pediatric patients with cytogenetically normal acute myeloid leukemia (CN-AML) and explore the clinical significances of these mutations. METHOD: Between August 2009 and December 2012, 30 children (<16 years old) with newly diagnosed CN-AML...
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