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Article

[A study of NPM1 and FLT3 gene mutations in acute myeloid leukemia].

Zhonghua nei ke za zhi - 1 Nov 2007

Wu De-pei, Yan Ling-zhi, Yang Li, Chen Su-ning, Wu Xiao-jin, Liang Jian-ying

Abstract excerpt

OBJECTIVE: To evaluate the prevalence and impact of NPM1 gene mutations and FLT3 internal tandem duplication (ITD) mutations in acute myeloid leukemia (AML). METHODS: Mononuclear cells in bone marrow samples were collected from 86 adult patients with newly diagnosed AML. FLT3 and NPM1 genes were amplified with genomic DNA-PCR. NPM1 exon-12 mutations were evaluated with capillary electrophoresis and FLT3-ITD...

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Source

Identifiers

PMID: 18261272

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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