Article
[Clinical characteristics of newly diagnosed acute myeloid leukemia patients with NPM1 mutation].
Zhongguo shi yan xue ye xue za zhi - 1 Feb 2014
Wei Hui, Zhang Yi-Qun, Lin Dong, Wang Ying, Zhou Chun-Lin, Liu Bing-Cheng, Li Wei, Rao Qing, Wang Min, Mi Ying-Chang, Wang Jian-Xiang
Abstract excerpt
The purpose of this study was to investigate the clinical characteristics of newly diagnosed acute myeloid leukemia (AML) patients with NPM1 mutation in exon 12 and to explore the relationship between NPM1 mutation and FLT3-ITD, IDH1 mutation. The AML clinical data and bone marrow samples of patients were collected. The diagnosis and classification were based on WHO criteria. The genomic DNA was extracted and...
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