Article
[The clinical characteristics of newly diagnosed acute myeloid leukemia patients with NPM1 mutation].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 May 2010
Zhu Hong-Hu, Jiang Bin, Lu Xi-Jing, Jiang Qian, Jiang Hao, Bao Li, Zhang Xiao-Hui, Lu Jin, Ruan Guo-Rui, Lai Yue-Yun, Liu Yan-Rong, Huang Xiao-Jun
Abstract excerpt
OBJECTIVE: To investigate the clinical characteristics of newly diagnosed acute myeloid leukemia (AML) with NPM1 mutation. METHODS: NPM1 mutation (including A, B, D mutation type) was detected in 206 patients with newly diagnosed AML by real-time quantitative RT-PCR. RESULTS: The incidence of NPM1 mutation was 15.5% in total AML patients and 32.5% in normal karyotypes AML patients. The characteristics of 174 NPM1...
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