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Article

Genome-wide interrogation identifies YAP1 variants associated with survival of small-cell lung cancer patients.

Cancer research - 1 Dec 2010

Wu Chen, Xu Binghe, Yuan Peng, Miao Xiaoping, Liu Yu, Guan Yin, Yu Dianke, Xu Jian, Zhang Tongwen, Shen Hongbing, Wu Tangchun, Lin Dongxin

Abstract excerpt

Although most patients with small-cell lung cancer respond to chemotherapy, the survival time is highly diverse. We conducted a genome-wide analysis to examine whether germline genetic variations are prognostic factors in small-cell lung cancer patients treated with the same chemotherapy regimen. Genome-wide scan of single nucleotide polymorphisms (SNP) was performed using blood DNA to identify genotypes...

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Source

Identifiers

PMID: 21118971
DOI: 10.1158/0008-5472.CAN-10-1493

Genes

YAP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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