Article
Association of GWAS-identified lung cancer susceptibility loci with survival length in patients with small-cell lung cancer treated with platinum-based chemotherapy.
PloS one - 1 Jan 2014
Li Dong, Wei Lixuan, Xu Binghe, Yu Dianke, Chang Jiang, Yuan Peng, Du Zhongli, Tan Wen, Shen Hongbing, Wu Tangchun, Wu Chen, Lin Dongxin
Abstract excerpt
Genetic variants have been shown to affect length of survival in cancer patients. This study explored the association between lung cancer susceptibility loci tagged by single-nucleotide polymorphisms (SNPs) identified in the genome-wide association studies and length of survival in small-cell lung cancer (SCLC). Eighteen SNPs were genotyped among 874 SCLC patients and Cox proportional hazards regression was used...
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