Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide examination of genetic variants associated with response to platinum-based chemotherapy in patients with small-cell lung cancer.

Pharmacogenetics and genomics - 1 Jun 2010

Wu Chen, Xu Binghe, Yuan Peng, Ott Jurg, Guan Yin, Liu Yu, Liu Zhe, Shen Yuanyuan, Yu Dianke, Lin Dongxin

Abstract excerpt

OBJECTIVES: Small-cell lung cancer (SCLC) accounts for about 20% of total lung cancer, and systemic chemotherapy is the major therapy for all stages of SCLC. Although most SCLC patients are characterized by initial chemosensitivity to the standard first-line platinum-based regimens, a significant fraction of patients are intrinsic nonresponders. METHODS: Genome-wide scan of 440 093 single-nucleotide polymorphisms...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carboplatin
Share to Cisplatin

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Etoposide

Share to Platinum

Share to R-SNARE Proteins

Share to Small Cell Lung Carcinoma

Source

Identifiers

PMID: 20463552
DOI: 10.1097/FPC.0b013e32833a6890

Genes

BCR
BTBD3
STXBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide examination of genetic variants associated with response to platinum-based chemotherapy in patients with small-cell lung cancer.PMID 20463552Read ↗

Genetic Variants Associated With Response to Platinum-Based Chemotherapy in Non-Small Cell Lung Cancer Patients: A Field Synopsis and Meta-Analysis.Semantic proximity Read ↗

Genome-wide association study of prognosis in advanced non-small cell lung cancer patients receiving platinum-based chemotherapy.Semantic proximity Read ↗

Applications of Machine Learning to Predict Cisplatin Resistance in Lung CancerSemantic proximity Read ↗

Cisplatin resistance-related transcriptome and methylome integration identifies PCDHB4 as a novel prognostic biomarker in small cell lung cancerSemantic proximity Read ↗

[Comprehensive Genomic Analysis for Small Cell Lung Cancer].Semantic proximity Read ↗

A genome-wide association study of survival in small-cell lung cancer patients treated with irinotecan plus cisplatin chemotherapy.Semantic proximity Read ↗

Genetic Polymorphisms and Platinum-based Chemotherapy Treatment Outcomes in Patients with Non-Small Cell Lung Cancer: A Genetic Epidemiology Study Based Meta-analysis.Semantic proximity Read ↗

Gene-gene and gene-environment interactions influence platinum-based chemotherapy response and toxicity in non-small cell lung cancer patientsSemantic proximity Read ↗

Genomic Features of Chinese Small Cell Lung CancerSemantic proximity Read ↗

Genomic features of Chinese small cell lung cancer.Semantic proximity Read ↗

THSD7B Mutation Induces Platinum Resistance in Small Cell Lung Cancer Patients.Semantic proximity Read ↗

Genetic variation predicting cisplatin cytotoxicity associated with overall survival in lung cancer patients receiving platinum-based chemotherapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.