Article
Exome-Wide Association Study Identifies Low-Frequency Coding Variants in 2p23.2 and 7p11.2 Associated with Survival of Non-Small Cell Lung Cancer Patients.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Apr 2017
Zhu Meng, Geng Liguo, Shen Wei, Wang Yuzhuo, Liu Jia, Cheng Yang, Wang Cheng, Dai Juncheng, Jin Guangfu, Hu Zhibin, Ma Hongxia, Shen Hongbing
Abstract excerpt
INTRODUCTION: A growing body of evidence has suggested that low-frequency or rare coding variants might have strong effects on the development and prognosis of cancer. Here, we aim to assess the role of low-frequency and rare coding variants in the survival of NSCLC in Chinese populations. METHODS: We performed an exome-wide scan of 247,870 variants in 1008 patients with NSCLC and replicated the promising...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
