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Article

Genomic profiling in advanced stage non-small-cell lung cancer patients with platinum-based chemotherapy identifies germline variants with prognostic value in SMYD2.

Cancer treatment and research communications - 1 Jan 2018

Galván-Femenía Iván, Guindo Marta, Duran Xavier, Calabuig-Fariñas Sílvia, Mercader Josep Maria, Ramirez Jose Luis, Rosell Rafael, Torrents David, Carreras Anna, Kohno Takashi, Jantus-Lewintre Eloisa, Camps Carlos, Perucho Manuel, Sumoy Lauro, Yokota Jun, de Cid Rafael

Abstract excerpt

OBJECTIVE: The aim of the study was to investigate the relationship between germline variations as a prognosis biomarker in patients with advanced Non-Small-Cell-Lung-Cancer (NSCLC) subjected to first-line platinum-based treatment. MATERIALS AND METHODS: We carried out a two-stage genome-wide-association study in non-small-cell lung cancer patients with platinum-based chemotherapy in an exploratory sample of 181...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30207284
DOI: 10.1016/j.ctarc.2018.02.003

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